Antibody responses in mice stimulated by various doses of the potato-derived major surface antigen of hepatitis B virus.

نویسندگان

  • Jung Won Youm
  • Young Suk Won
  • Jae Heung Jeon
  • Ki Beom Moon
  • Hyoung Chin Kim
  • Kee-Sun Shin
  • Hyouk Joung
  • Hyun Soon Kim
چکیده

The ability of potato-derived major surface antigen of hepatitis B virus (P-HBsAg) to elicit antibody responses to different dosages of P-HBsAg ranging from 0.02 to 30 μg administered orally in mice was examined. All immunized groups produced specific serum IgG and fecal IgA antibodies against P-HBsAg, even at low levels (<5 μg), after administration of a 0.5-μg yeast-derived HBsAg (Y-HBsAg; LG Life Sciences, Republic of Korea) booster.

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عنوان ژورنال:
  • Clinical and vaccine immunology : CVI

دوره 17 12  شماره 

صفحات  -

تاریخ انتشار 2010